CICA PDRN refers to a plant-derived form of polydeoxyribonucleotide (PDRN), a chain of DNA fragments known for their regenerative and skin-repairing properties. CICA PDRN is extracted from the Centella asiatica plant, a botanical widely recognized for its soothing and healing effects. Like other nucleic acid–based actives, it works by supporting the skin’s natural repair processes, encouraging cell renewal, and enhancing collagen production. This regenerative action helps strengthen weakened skin, calm irritation, and promote healthier tissue recovery, making it a gentle yet highly effective option for sensitive or compromised skin.